Leilani Mitchell was on fire to start the game with 10 points during the first five minutes for Arras. The home fans were making plenty of noise as their team led (13-7).
Villeneuve managed to stay in the match with their shooting behind the arc, 4-from-8, as they finished the first quarter trailing just 7 points (17-25).
Carla Thomas continued the three-point shooting festival for Villeneuve to open the scoring at the start of the second quarter.
However Arras stretched their advantage into double digits with back to back scores from Marielle Amant and Mitchell (31-20) with 12 minutes played.
Ingrid Tanqueray's (right) perfect shooting from beyond the arc and Olayinka Sanni's work inside the paint brought Villeneue to within 5 points (35-40) with 90 seconds left before the break.
Mitchell's pace and Olesia Malashenko's finishing enabled Arras to go into the locker room with a 9-point advantage (44-35).
Villeneuve were more aggressive at the start of the third quarter and reduced the deficit to 2 points (49-51) thanks to Emilie Gomis midway through the third quarter.
Mitchell seemed to be the only player enjoying the heat and she quickly restored a 7-point lead with a shot from the land of many with her 24th point of the game (58-51).
Mitchell hit her third trey of the match to push the lead back into double digits but Villeneuve had to thank Tanqueray with her fifth trey of the game (57-63) in reducing the deficit to 6 points going into the final quarter.
Marielle Amant opened the scoring in the final quarter but once again Tanqueray replied with a trey.
Villeneuve stepped up a gear and started to take risks as they fought to bring the score down. Yet they were unable to stop Mitchell.
Mitchelll went 4-of-4 from the charity stripes and then delivered the perfect pass to Malashenko who hit a trey.
Malashenko then took over the scoring with back to back scores for Arras to lead (84-72) with just over three minutes to play.
Villeneuve managed to reduce the deficit but ended up losing for the fifth time this season to Arras.
Mitchell finished the match with 31 points, 5 assists and 3 steals for the LFB award of player of the match.
Basket Landes had more or less booked their ticket for the semi-final by winning the first game by 24 points. Basket Landes gave the home supporters something to cheer about with extending their LFB winning streak to nine games.
Basket Landes 87-61 Aix-en-Provence
Basket Landes: Aminata Konate 7 (8 rebounds), Katarina Manic 4, Bineta Diouf 6, Anaïs Le Gluher 11, Julie Barennes 8, Julia Borde 10, Marion Laborde 10, Laurie Lapeyre 13, Marion Pujos 6, Jennifer Humphrey 12